I'm having an issue where a computer that was seemingly working fine a couple days ago is now freezing whenever I try to click on anything on the desktop. This happens right after startup. I can sometimes get the start menu to open, but once I try to click on any icon in the start menu, it freezes again. I thought it was Kaspersky at first so I went into safe mode and turned off a ton of start up programs, but the problem still continues. I did a system restore that seemed to work for a little while but the problem continues. I can do almost anything in safe mode. I went in and copied all the documents and settings onto my external so I can move them to another computer, I have had no problem at all.
I should also note that the mouse still moves and the hard drive light still randomly flashes as if it's trying to access something. Also, the hard drive is fairly full, it's a 40GB hard drive and has about 300MB left on it. I don't know if that would make a difference, except maybe in the page file.
The computer is a Dell Inspiron 9300 running XP Professional, SP3, with 2GB of RAM.