IIS does not as far as i can remember (I haven’t played with newer version)
Support multiple virtual DOMAINS...
Do what I do, Win 2000 and 2003 servers are over rated.
Use a simple windows 2000 pro OS or Windows XP Pro, install apache for windows along with PHP and MySQL.
You'll never regret it, it's by far the simplest and easiest and most manageable setup you can ever use.
Keep in mind I’m not a Microsoft fan, i would choose Linux over windows any day, but the fact remain for people who don’t have the time to learn and manage the Linux OS and are more familiar with windows, do it my way.