I'm setting up my server to host 2 domains. In the VirtualHosts section I have it set up as they do on the Apache website. But line 280 or so asks for a DocumentRoot, well I have 2, what should I do here?

You have to make two separate entries in the httpd.conf file like this:

NameVirtualHost *:80

<VirtualHost *:80>
        ServerAdmin webmaster@srvr4.txlinux.com
        DocumentRoot /var/www/html/txlinux.com
        ServerName srvr4.txlinux.com
        ServerAlias www.srvr4.txlinux.com
        ErrorLog logs/txlinux.com-error_log
        CustomLog logs/txlinux.com-access_log common

<VirtualHost *:80>
        ServerAdmin webmaster@cherryoak.com
        DocumentRoot /var/www/html/cherryoak.com
        ServerName cherryoak.com
        ServerAlias www.cherryoak.com
        ErrorLog logs/cherryoak.com-error_log
        CustomLog logs/cherryoak.com-access_log common

The NameVirtualHost *:80 above the first entry tell apache witch site is the default for the server if no URL is given just the IP address.