I have a few Macs in my group that fail to print to PDF using Acrobat's Distiller 7 driver. On these Macs, I can save as PDF from the print dialog, but have to be able to print to PDF for workflows. Upgrading to Acrobat 8 solves the issue, but we have to stay at 7 for a few months still. These Macs had the same issue when using CS2.
10.4.11, Active Directory, Office 04, Adobe CS3 (Acrobat 7 instead of 8),Quark XPress 6.52 , heavy AppleScript use for workflows