I would say bring the resolution down to something more reasonable. Just because the monitor will work at that high a resolution does not mean you have to use it. The reason the game runs slow is there is not enough memory on the video card to keep up with the resolution at that high a setting so turn it down to 1650 x 1024 and let the video card control frequency. If you have a DVI port on the card then use the DVI instead of the Analog port and you will see a difference.
rch1231 169 Posting Shark