I am getting this int he Application log on one of our servers

Source: Alert Manager Event Interface
EventID: 257

Alert Manager Event Interface: Alert Manager Event Interface unable to send alert to \\SBS2KSVR\pipe\AlertManager. Error returned = The system cannot find the file specified.

I have checked and the Alert Manager services is not running so I start it and it just stops.

It is also set to start automatically.

Any ideas?

Go to the Virus Scan AlertingConfiguration panel.
Check the radio button for "Enable centralized alerting."
Click on Configure, and browse the the alert location.
Check to see if you're running VirusScan Alert Manager as the SYSTEM account. SYSTEM can't use network drives since it is a localmachine account.

Paraphrased from: http://www.tek-tips.com/viewthread.cfm?qid=608912

Good Luck

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