at power up front without pressing any key exits the BIOS setup, you must do

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Thread indicates the system is leaving the UEFI/BIOS on power-up and the OP can only get back in by pressing a key. That matches ’s report; ’s comment about using a key is a useful start but is imprecise for an Asus H81M-A. Desktop Asus boards normally use the Delete key (sometimes F2) to enter setup — tap the key repeatedly from the instant the machine is powered on rather than holding it down.

If tapping Delete/F2 does nothing, work through these practical checks before assuming a motherboard fault:

  • Use a wired keyboard on a rear USB 2.0 port (front ports or USB 3.0 ports sometimes aren’t initialized early enough). A PS/2 keyboard (or adapter) is even more reliable for entering BIOS on old boards.
  • Disconnect all USB devices and removable drives to rule out a stuck-key or peripheral that’s sending input at POST.
  • If the board quickly boots past setup or behaves as if settings are lost between boots, clear the CMOS: power off, unplug PSU, remove the CR2032 coin cell for several minutes (or use the motherboard’s clear-jumper per the manual), press and hold the case power button for a few seconds to discharge, then reinstall battery and boot.

Once able to enter setup, disable Fast Boot so the keyboard is available on future POSTs and set the date/time, save, and exit. If the problem persists after a CMOS clear and trying a different keyboard/port, replace the CMOS battery and consider updating the BIOS using Asus’ EZ Flash tool from inside UEFI or the support page. Check front-panel power/reset wiring too; a miswired/reset switch can cause odd behavior.

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Most systems will enter the bios setup if you hold down any key (like esc) when starting to boot.

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