A few days ago I found that I was no longer able to use application functions that access (browse) the system file directory...such as the OPEN buttons...the SAVE AS function....downloading or uploading files...etc.

Any ideas?

Windows Vista Home Premium - 64bit - SP2

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This could be either the run32.exe virus or a scvhost.exe duplicate.
Do you find that your taskbar changes from windows aero to windows classic unexpectantly by any chance? This may help with the solving of the problem?

hi ,, i get that ,, i hav this problem your talking about, i have vista and i cant download or open the programs on my laptop ,, like movie maker ,, do u think its a virus ?

Try doing a scan with malware bytes. See here. Are you the admin user?

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