Renos.y is the name of the trojan that my AV software picked up (trend micro antivirus), but it's unable to delete the Trojan and I can’t open the drive D, E, F. so what do i do now?

Maybe I should reinstall my computer and restore the data with EASEUS data recovery wizard or other data recovery programs.

Hie, please back up your files first and try cleaning your machine usig another antivirus software. If all these alternatives fail, format the Hard drive.

dont forget to disable system restore before cleaning your computer...that may also be the reason you cannot delete the trojan. If you don't disable system restore, the trojan will just come back.