System32 opening on startup is caused by a line on the startup tab of msconfig. Go to Start|Run|type msconfig and click OK. On the startup tab, look for /L:ENG. If found, uncheck it. That entry is associated with the SB Audigy 2. To remove the entry from the Startup tab go to Start|All Programs|Creative|Sound Blaster|Audigy 2|Welcome Message. Check “Do not show this again.”
In the event this problem is occurring and no Audigy sound card is installed, the procedures above will not be available. In that case, see if the information here is helpful.